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192.168.6.56/handle/123456789/77469| Title: | Molecular and Functional Insights Into the Pulmonary Vasculature |
| Authors: | Parthasarathi, Kaushik |
| Keywords: | biology |
| Issue Date: | 2018 |
| Publisher: | Springer International Publishing AG |
| Description: | Lung morphogenesis is a highly orchestrated process beginning with the appearance of lung buds on approximately embryonic day 9.5 in the mouse. Endodermally derived epithelial cells of the primitive lung buds undergo branching morphogenesis to generate the tree-like network of epithelial-lined tubules. The pulmonary vasculature develops in close proximity to epithelial progenitor cells in a process that is regulated by interactions between the developing epithelium and underlying mesenchyme. Studies in transgenic and knockout mouse models demonstrate that normal lung morphogenesis requires coordinated interactions between cells lining the tubules, which end in peripheral saccules, juxtaposed to an extensive network of capillaries. Multiple growth factors, microRNAs, transcription factors |
| URI: | http://10.6.20.12:80/handle/123456789/77469 |
| ISBN: | 978-3-319-68482-6 |
| Appears in Collections: | Biology |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kaushik Parthasarathi_2018.pdf | 2.07 MB | Adobe PDF | View/Open |
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