Please use this identifier to cite or link to this item: 192.168.6.56/handle/123456789/75031
Title: Flow Chemistry for the Synthesis of Heterocycles
Authors: K. Sharma, Upendra
Eycken, Erik V. Van der
Keywords: Synthesis of Heterocycles
Issue Date: 2018
Publisher: Springer International Publishing AG
Description: The heterocyclic ring is the most prevalent structural motif in the majority of natural products, pharmaceuticals as well as agrochemicals and shows tuneable interactions with biological targets besides conferring a degree of structural and metabolic stability. Heterocyclic chemistry can be regarded as an inexhaustible source of novel compounds due to the vast number of possible combinations of carbon, hydrogen and heteroatoms. Due to increased environmental concern and the impact of their work, synthetic chemists are actively responding to the so-called green agenda. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods such as drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions and safe handling of hazardous and obnoxious materials. Such recent technological developments to alleviate the labour-intensive practices in chemical industry encouraged us to compile a volume especially towards the application of flow chemistry in heterocyclic synthesis. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, an update to its predecessor (Organometallic flow chemistry) was well warranted.
URI: http://10.6.20.12:80/handle/123456789/75031
ISBN: 978-3-319-94328-2
Appears in Collections:Chemistry

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