Title:	Advancing Development of Synthetic Gene Regulators
Authors:	Chandran, Anandhakumar
Keywords:	Synthetic Gene Regulators
Issue Date:	2016
Publisher:	Springer Nature Singapore Pte Ltd
Description:	Next-generation-sequencing (NGS) technologies enable us to obtain extensive information by deciphering millions of individual DNA sequencing reactions simultaneously. The new DNA-sequencing strategies exceed their precursors in output by many orders of magnitude, resulting in a quantitative increase in valuable sequence information that could be harnessed for qualitative analysis. Sequencing on this scale has facilitated significant advances in diverse disciplines, ranging from the discovery, design, and evaluation of many small molecules and relevant biological mechanisms to maturation of personalized therapies. NGS technologies that have recently become affordable allow us to gain in-depth insight into small-molecule-triggered biological phenomena and empower researchers to develop advanced versions of small molecules. In this chapter we focus on the overlooked implications of NGS technologies in chemical biology, with a special emphasis on small-molecule development and screening.
URI:	http://10.6.20.12:80/handle/123456789/74750
ISBN:	978-981-10-6547-7 978-981-10-6547-7
Appears in Collections:	Chemistry

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.