Please use this identifier to cite or link to this item: 192.168.6.56/handle/123456789/74750
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dc.contributor.authorChandran, Anandhakumar-
dc.date.accessioned2019-07-02T06:10:12Z-
dc.date.available2019-07-02T06:10:12Z-
dc.date.issued2016-
dc.identifier.isbn978-981-10-6547-7-
dc.identifier.isbn978-981-10-6547-7-
dc.identifier.urihttp://10.6.20.12:80/handle/123456789/74750-
dc.descriptionNext-generation-sequencing (NGS) technologies enable us to obtain extensive information by deciphering millions of individual DNA sequencing reactions simultaneously. The new DNA-sequencing strategies exceed their precursors in output by many orders of magnitude, resulting in a quantitative increase in valuable sequence information that could be harnessed for qualitative analysis. Sequencing on this scale has facilitated significant advances in diverse disciplines, ranging from the discovery, design, and evaluation of many small molecules and relevant biological mechanisms to maturation of personalized therapies. NGS technologies that have recently become affordable allow us to gain in-depth insight into small-molecule-triggered biological phenomena and empower researchers to develop advanced versions of small molecules. In this chapter we focus on the overlooked implications of NGS technologies in chemical biology, with a special emphasis on small-molecule development and screening.en
dc.languageenen
dc.languageenen
dc.language.isoenen_US
dc.publisherSpringer Nature Singapore Pte Ltden_US
dc.subjectSynthetic Gene Regulatorsen_US
dc.titleAdvancing Development of Synthetic Gene Regulatorsen_US
dc.typeBooken_US
Appears in Collections:Chemistry

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