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192.168.6.56/handle/123456789/3079| Title: | "Genomics and Systems Biology of mammalin cell culter " |
| Authors: | M. Berger Scheper, Prof. Dr. T. |
| Keywords: | Biology |
| Issue Date: | 2012 |
| Publisher: | Springe |
| Description: | Mammalian cell cultures are the dominating production system of today’s biopharmaceutic products. The increasing emphasis on product quality and the demand for greater cost-efficiency and process robustness call for better fundamental understanding on cell, process and product. Whereas physiological manipulation and bioprocess renovation have played a pivotal role to the success of cell culture biomanufacturing in the past, genomic and systems approaches will drive the next innovations in mammalian cell culture technology. Genome-wide analysis of the genetic information, gene expression, signaling network and metabolism, along with the integration of vast experimental data and mathematical tools will afford a holistic and quantitative understanding of cellular processes and lead to quality products and robust processes. Although somewhat lagging behind life sciences and biomedicine, systems biology application to cell culture technology is gaining its momentum. |
| URI: | http://10.6.20.12:80/handle/123456789/3079 |
| ISBN: | 978-3-642-28349-9 |
| Appears in Collections: | Veterinary Medicine |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 48.pdf.pdf | 4.98 MB | Adobe PDF | View/Open |
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