Please use this identifier to cite or link to this item: 192.168.6.56/handle/123456789/77468
Title: Argonaute Proteins
Authors: Katsutomo, Kotaro Nakanishi
Okamura, Katsutomo
Keywords: biology
Issue Date: 2018
Publisher: Springer Science+Business Media LLC
Description: Since the discovery that Argonautes play essential roles in RNA silencing in a variety of eukaryotes, biochemical properties and biological functions of Argonautes have been extensively studied using an assortment of techniques [1, 3]. Biochemical and structural analyses in the past decade clarified their detailed molecular architectures along with the mechanisms by which Argonautes bind guide and target nucleic acids and cleave targets [4, 5]. Despite the similarity of the overall domain structures, the roles of eukaryotic and prokaryotic Argonautes are quite diverse. Most of them seem to serve mainly as defense systems against foreign nucleic acids, such as viruses/bacteriophages and transposons, while some others are involved in gene regulation
URI: http://10.6.20.12:80/handle/123456789/77468
ISBN: 978-1-4939-7338-5
Appears in Collections:Biology

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