Please use this identifier to cite or link to this item:
192.168.6.56/handle/123456789/74859| Title: | CFTR and Cystic Fibrosis |
| Authors: | M. Farinha, Carlos |
| Keywords: | Cystic Fibrosis |
| Issue Date: | 2018 |
| Publisher: | Springer imprint is published by Springer Nature |
| Description: | Cystic fibrosis (CF) is a monogenic autosomal recessive disorder that affects Caucasian individuals. Clinically it is characterized by chronic pulmonary dysfunction, pancreatic insufficiency, increased saline concentration in sweat, and male infertility. The gene responsible for the disease was cloned in 1989 and encodes an ABC transporter, the 1480-amino acid protein named Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), that functions as a chloride (Cl-) channel in the apical membrane of epithelial cells. |
| URI: | http://10.6.20.12:80/handle/123456789/74859 |
| ISBN: | 978-3-319-65494-2 |
| Appears in Collections: | Chemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2018_Book_CFTRAndCysticFibrosis.pdf | 1.75 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.