Title:	Biotransformations in Organic Chemistry
Authors:	Faber, Kurt
Keywords:	Organic Chemistry
Issue Date:	2018
Publisher:	Springer International Publishing AG
Description:	The use of natural catalysts – enzymes – for the transformation of nonnatural man-made organic compounds is not at all new: they have been used for more than 100 years, employed either as whole cells or isolated enzymes. While the object of the early research was the elucidation of biochemical pathways and enzyme mechanisms, it was the steep rise of asymmetric synthesis during the 1980s that the enormous potential of enzymes for the synthesis of nonnatural organic compounds was recognized. What started as an academic curiosity in the late 1970s became a hot topic in synthetic organic chemistry in the 1990s. Driven by breathtaking developments in molecular biosciences, the search for novel enzymes, their production, and adaptation to industrial processes are continuously simplified, which is demonstrated by the wavelike appearance of novel biocatalytic principles. As a result of this extensive research, there have been an estimated 18,000 papers published on the subject to date. To collate these data as a kind of “super-review” would clearly be an impossible task, and, furthermore, such a hypothetical book would be unpalatable for the non-expert.
URI:	http://10.6.20.12:80/handle/123456789/74815
ISBN:	978-3-319-61590-5
Appears in Collections:	Chemistry

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